Progressive, transgenerational changes in offspring phenotype and epigenotype following nutritional transition.

Induction of altered phenotypes during development in response to environmental input involves epigenetic changes. Phenotypic traits can be passed between generations by a variety of mechanisms, including direct transmission of epigenetic states or by induction of epigenetic marks de novo in each ge...

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Bibliographic Details
Main Authors: Graham C Burdge, Samuel P Hoile, Tobias Uller, Nicola A Thomas, Peter D Gluckman, Mark A Hanson, Karen A Lillycrop
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3227644?pdf=render