Characterizing the role of atrial natriuretic peptide signaling in the development of embryonic ventricular conduction system

Abstract Patients born with congenital heart defects frequently encounter arrhythmias due to defects in the ventricular conduction system (VCS) development. Although recent studies identified transcriptional networks essential for the heart development, there is scant information on the mechanisms r...

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Bibliographic Details
Main Authors: Arun Govindapillai, Adam Hotchkiss, Mark Baguma-Nibasheka, Robert A. Rose, Lucile Miquerol, Oliver Smithies, Nobuyo Maeda, Kishore B. S. Pasumarthi
Format: Article
Language:English
Published: Nature Publishing Group 2018-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-25292-0