Wtip and Vangl2 are required for mitotic spindle orientation and cloaca morphogenesis

Wtip and Vangl2 are required for mitotic spindle orientation and cloaca morphogenesis

Summary Defects in cilia and basal bodies function are linked to ciliopathies, which result in kidney cyst formation. Recently, cell division defects have been observed in cystic kidneys, but the underlying mechanisms of such defects remain unclear. Wtip is an LIM domain protein of the Ajuba/Zyxin f...

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Bibliographic Details
Main Authors: Ekaterina Bubenshchikova, Koichiro Ichimura, Yayoi Fukuyo, Rebecca Powell, Chaonan Hsu, Stephen O. Morrical, John R. Sedor, Tatsuo Sakai, Tomoko Obara
Format: Article
Language:English
Published: The Company of Biologists 2012-05-01
Series:Biology Open
Subjects:
Ciliopathies
Mitotic spindle
Basal body
Zebrafish
Online Access:http://bio.biologists.org/content/1/6/588

Internet

http://bio.biologists.org/content/1/6/588

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