Impact of Dissolved Oxygen during UV-Irradiation on the Chemical Composition and Function of CHO Cell Culture Media.

Ultraviolet (UV) irradiation is advantageous as a sterilization technique in the biopharmaceutical industry since it is capable of targeting non-enveloped viruses that are typically challenging to destroy, as well as smaller viruses that can be difficult to remove via conventional separation techniq...

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Bibliographic Details
Main Authors: Sarah M Meunier, Biljana Todorovic, Emma V Dare, Afroza Begum, Simon Guillemette, Andrew Wenger, Priyanka Saxena, J Larry Campbell, Michael Sasges, Marc G Aucoin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4790850?pdf=render