Computational modeling with forward and reverse engineering links signaling network and genomic regulatory responses: NF-κB signaling-induced gene expression responses in inflammation
<p>Abstract</p> <p>Background</p> <p>Signal transduction is the major mechanism through which cells transmit external stimuli to evoke intracellular biochemical responses. Diverse cellular stimuli create a wide variety of transcription factor activities through signal t...
Main Authors: | Peng Chien, Chao Chun, Chen Yan, Tung Kai, Wong David, Peng Shih, Chuang Yung, Tang Chuan |
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Format: | Article |
Language: | English |
Published: |
BMC
2010-06-01
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Series: | BMC Bioinformatics |
Online Access: | http://www.biomedcentral.com/1471-2105/11/308 |
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