Computational modeling with forward and reverse engineering links signaling network and genomic regulatory responses: NF-κB signaling-induced gene expression responses in inflammation

<p>Abstract</p> <p>Background</p> <p>Signal transduction is the major mechanism through which cells transmit external stimuli to evoke intracellular biochemical responses. Diverse cellular stimuli create a wide variety of transcription factor activities through signal t...

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Bibliographic Details
Main Authors: Peng Chien, Chao Chun, Chen Yan, Tung Kai, Wong David, Peng Shih, Chuang Yung, Tang Chuan
Format: Article
Language:English
Published: BMC 2010-06-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/11/308