A combined quantitative mass spectrometry and electron microscopy analysis of ribosomal 30S subunit assembly in E. coli

Ribosome assembly is a complex process involving the folding and processing of ribosomal RNAs (rRNAs), concomitant binding of ribosomal proteins (r-proteins), and participation of numerous accessory cofactors. Here, we use a quantitative mass spectrometry/electron microscopy hybrid approach to deter...

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Bibliographic Details
Main Authors: Dipali G Sashital, Candacia A Greeman, Dmitry Lyumkis, Clinton S Potter, Bridget Carragher, James R Williamson
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-10-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/04491