Dl-3-n-Butylphthalide Ameliorates Diabetic Nephropathy by Ameliorating Excessive Fibrosis and Podocyte Apoptosis

Dl-3-n-Butylphthalide Ameliorates Diabetic Nephropathy by Ameliorating Excessive Fibrosis and Podocyte Apoptosis

Diabetic nephropathy (DN) is a common diabetes associated complication. Thus, it is important to understand the pathological mechanism of DN and find the appropriate therapeutic strategy for it. Dl-3-n-Butylphthalide (DL-NBP) has anti-inflammatory and antioxidant effects, and been widely used for th...

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Bibliographic Details
Main Authors: Jingyu Xu, Zonghao Tang, Youwu He, Shufang Cai, Beini Wang, Susu Zhang, Man Wu, Kai Qian, Kailun Zhang, Bo Chai, Guorong Chen, Ke Xu, Hao Ji, Jian Xiao, Yanqing Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Pharmacology
Subjects:
diabetic nephropathy
dl-3-n-butylphthalide
podocytes
endoplasmic reticulum stress
glomerular filtration barrier
vascular endothelial growth factor
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.628950/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.628950/full

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