Differential Constitutive and Cytokine-Modulated Expression of Human Toll-like Receptors in Primary Neutrophils, Monocytes, and Macrophages

<p>Human Toll-like receptors (TLRs) comprise a family of proteins that recognizes pathogen-associated molecular patterns (PAMPs) and initiates host innate immune responses. Neutrophils, monocytes, and macrophages are critical cellular components of the human innate immune system. Proinflammato...

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Bibliographic Details
Main Author: D. Shane O'Mahony, Uyenvy Pham, Ramesh Iyer, Thomas R. Hawn, W. Conrad Liles
Format: Article
Language:English
Published: Ivyspring International Publisher 2008-01-01
Series:International Journal of Medical Sciences
Online Access:http://www.medsci.org/v05p0001.htm