Effect of okadaic acid on cultured clam heart cells: involvement of MAPkinase pathways
Summary Okadaic acid (OA) is one of the main diarrhetic shellfish poisoning toxins and a potent inhibitor of protein phosphatases 1 and 2A. The downstream signal transduction pathways following the protein phosphatase inhibition are still unknown and the results of most of the previous studies are o...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2012-09-01
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Series: | Biology Open |
Subjects: | |
Online Access: | http://bio.biologists.org/content/1/12/1192 |