Inhibitory effects against α-glucosidase and α-amylase of the flavonoids-rich extract from Scutellaria baicalensis shoots and interpretation of structure–activity relationship of its eight flavonoids by a refined assign-score method

Inhibitory effects against α-glucosidase and α-amylase of the flavonoids-rich extract from Scutellaria baicalensis shoots and interpretation of structure–activity relationship of its eight flavonoids by a refined assign-score method

Abstract A flavonoids-rich extract of Scutellaria baicalensis shoots and its eight high content flavonoids were investigated for their inhibitory effects against α-glucosidase and α-amylase. Results show that abilities of the extract in inhibiting the two enzymes were obviously higher than those of...

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Bibliographic Details
Main Authors: Ke Li, Fan Yao, Qiang Xue, Hang Fan, Lingguang Yang, Xiang Li, Liwei Sun, Yujun Liu
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Chemistry Central Journal
Subjects:
Scutellaria baicalensis shoots
Flavonoids
α-Glucosidase
α-Amylase
Structure–activity relationship
Refined assign-score method
Online Access:http://link.springer.com/article/10.1186/s13065-018-0445-y

Internet

http://link.springer.com/article/10.1186/s13065-018-0445-y

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