Identification and classification of conserved RNA secondary structures in the human genome.

The discoveries of microRNAs and riboswitches, among others, have shown functional RNAs to be biologically more important and genomically more prevalent than previously anticipated. We have developed a general comparative genomics method based on phylogenetic stochastic context-free grammars for ide...

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Bibliographic Details
Main Authors: Jakob Skou Pedersen, Gill Bejerano, Adam Siepel, Kate Rosenbloom, Kerstin Lindblad-Toh, Eric S Lander, Jim Kent, Webb Miller, David Haussler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-04-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.0020033