KAT6A, a Chromatin Modifier from the 8p11-p12 Amplicon is a Candidate Oncogene in Luminal Breast Cancer

The chromosome 8p11-p12 amplicon is present in 12% to 15% of breast cancers, resulting in an increase in copy number and expression of several chromatin modifiers in these tumors, including KAT6A. Previous analyses in SUM-52 breast cancer cells showed amplification and overexpression of KAT6A, and...

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Bibliographic Details
Main Authors: Brittany Turner-Ivey, Stephen T. Guest, Jonathan C. Irish, Christiana S. Kappler, Elizabeth Garrett-Mayer, Robert C. Wilson, Stephen P. Ethier
Format: Article
Language:English
Published: Elsevier 2014-08-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558614000943