Therapeutic Targeting of Telomerase

Telomere length and cell function can be preserved by the human reverse transcriptase telomerase (hTERT), which synthesizes the new telomeric DNA from a RNA template, but is normally restricted to cells needing a high proliferative capacity, such as stem cells. Consequently, telomerase-based therapi...

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Bibliographic Details
Main Authors: Kathrin Jäger, Michael Walter
Format: Article
Language:English
Published: MDPI AG 2016-07-01
Series:Genes
Subjects:
Online Access:http://www.mdpi.com/2073-4425/7/7/39