Association of blood IgG with tumor necrosis factor-alpha and clinical course of chronic lymphocytic leukemiaResearch in context

The intrinsic humoral immunodeficiency of chronic lymphocytic leukemia (CLL) is often managed with immunoglobulin replacement therapy (IgRT) to maintain IgG levels in the low-normal range (6–8 g/L) but optimal targets for IgG and timing to commence IgRT are unclear. IgG levels fell near 6 g/L at rat...

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Bibliographic Details
Main Authors: David E. Spaner, Robertson Venema, Justin Huang, Peter Norris, Alan Lazarus, Guizhi Wang, Yonghong Shi
Format: Article
Language:English
Published: Elsevier 2018-09-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396418303384