Intracellular hydrogelation preserves fluid and functional cell membrane interfaces for biological interactions

Intracellular hydrogelation preserves fluid and functional cell membrane interfaces for biological interactions

Cell membrane interface is mostly studied using synthetic bilayers and reconstituted cell membranes. Here the authors present a new cell fixation method in which the cytoskeleton is replaced by a synthetic hydrogel polymer network assembled inside the cell, thereby preserving the fluid membrane prop...

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Bibliographic Details
Main Authors: Jung-Chen Lin, Chen-Ying Chien, Chi-Long Lin, Bing-Yu Yao, Yuan-I Chen, Yu-Han Liu, Zih-Syun Fang, Jui-Yi Chen, Wei-ya Chen, No-No Lee, Hui-Wen Chen, Che-Ming J. Hu
Format: Article
Language:English
Published: Nature Publishing Group 2019-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-09049-5

Internet

https://doi.org/10.1038/s41467-019-09049-5

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