Genetic Variations in the Promoter of the APE1 Gene Are Associated with DMF-Induced Abnormal Liver Function: A Case-Control Study in a Chinese Population

Acute or long-term exposure to N,N-dimethylformamide (DMF) can induce abnormal liver function. It is well known that DMF is mainly metabolized in the liver and thereby produces reactive oxygen species (ROS). The base excision repair (BER) pathway is regarded as a very important pathway involved in r...

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Bibliographic Details
Main Authors: Zhimin Tong, Huanxi Shen, Dandan Yang, Feng Zhang, Ying Bai, Qian Li, Jian Shi, Hengdong Zhang, Baoli Zhu
Format: Article
Language:English
Published: MDPI AG 2016-07-01
Series:International Journal of Environmental Research and Public Health
Subjects:
Online Access:http://www.mdpi.com/1660-4601/13/8/752