Indoleamine 2,3-Dioxygenase (IDO) Downregulates the Cell Surface Expression of the CD4 Molecule

Indoleamine 2,3-Dioxygenase (IDO) Downregulates the Cell Surface Expression of the CD4 Molecule

Indoleamine 2,3-dioxygenase (IDO) has been implicated in preventing the fetus from undergoing maternal T cell-mediated immune responses, yet the mechanism underlying these kinds of IDO-mediated immune responses has not been fully elucidated. Since the CD4 molecule plays a central role in the onset a...

Full description

Bibliographic Details
Main Authors: Lingfei Wu, Xiuyan Huang, Shuyun Zhao, Congrong Zhou, Peiyan Liang, Yaoying Zeng, Guanyou Huang, Xianhui He
Format: Article
Language:English
Published: MDPI AG 2012-08-01
Series:International Journal of Molecular Sciences
Subjects:
human IDO
CD4
T cell
immune tolerance
immune response
Online Access:http://www.mdpi.com/1422-0067/13/9/10863

Internet

http://www.mdpi.com/1422-0067/13/9/10863

Similar Items