AOPPs Induce MCP-1 Expression by Increasing ROS-Mediated Activation of the NF-κB Pathway in Rat Mesangial Cells: Inhibition by Sesquiterpene Lactones

AOPPs Induce MCP-1 Expression by Increasing ROS-Mediated Activation of the NF-κB Pathway in Rat Mesangial Cells: Inhibition by Sesquiterpene Lactones

Background: Monocyte chemoattractant protein-1 (MCP-1) plays an important role in extracellular matrix accumulation through macrophage recruitment and activation in the development and progression of diabetic nephropathy. Therefore, this study examined whether advanced oxidation protein products (AO...

Full description

Bibliographic Details
Main Authors: Jian-Cheng Wang, Yan Zhao, Si-Jia Chen, Jing Long, Qian-Qian Jia, Jia-Dai Zhai, Quan Zhang, Yue Chen, Hai-Bo Long
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2013-12-01
Series:Cellular Physiology and Biochemistry
Subjects:
MCP-1
Advanced oxidation protein products
Reactive oxygen species
Nuclear factor-kappa B
Sesquiterpene lactones
Online Access:http://www.karger.com/Article/FullText/356619

Internet

http://www.karger.com/Article/FullText/356619

Similar Items