Weighted Gene Co-expression Network Analysis Identifies a Cancer-Associated Fibroblast Signature for Predicting Prognosis and Therapeutic Responses in Gastric Cancer

Weighted Gene Co-expression Network Analysis Identifies a Cancer-Associated Fibroblast Signature for Predicting Prognosis and Therapeutic Responses in Gastric Cancer

Background: Cancer-associated fibroblasts (CAFs) are the most prominent cellular components in gastric cancer (GC) stroma that contribute to GC progression, treatment resistance, and immunosuppression. This study aimed at exploring stromal CAF-related factors and developing a CAF-related classifier...

Full description

Bibliographic Details
Main Authors: Hang Zheng, Heshu Liu, Huayu Li, Weidong Dou, Xin Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Molecular Biosciences
Subjects:
gastric cancer
cancer-associated fibroblasts
weighted gene co-expression network analysis
biomarker
prognosis
immunotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.744677/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2021.744677/full

Similar Items