LH and hCG action on the same receptor results in quantitatively and qualitatively different intracellular signalling.

LH and hCG action on the same receptor results in quantitatively and qualitatively different intracellular signalling.

Human luteinizing hormone (hLH) and chorionic gonadotropin (hCG) act on the same receptor (LHCGR) but it is not known whether they elicit the same cellular and molecular response. This study compares for the first time the activation of cell-signalling pathways and gene expression in response to hLH...

Full description

Bibliographic Details
Main Authors: Livio Casarini, Monica Lispi, Salvatore Longobardi, Fabiola Milosa, Antonio La Marca, Daniela Tagliasacchi, Elisa Pignatti, Manuela Simoni
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3465272?pdf=render

Internet

http://europepmc.org/articles/PMC3465272?pdf=render

Similar Items