A pretargeting system for tumor PET imaging and radioimmunotherapy

A pretargeting system for tumor PET imaging and radioimmunotherapy

Labeled antibodies, as well as their fragments and antibody-derived recombinant constructs, have long been proposed as general vectors to target radionuclides to tumor lesions for imaging and therapy. They have indeed shown promise in both imaging and therapeutic applications, but they have not fulf...

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Bibliographic Details
Main Authors: Françoise eKraeber-Bodéré, Caroline eRousseau, Caroline eBodet-milin, Eric eFrampas, Alain eFaivre-Chauvet, Aurore eRauscher, Robert eSharkey, David eGoldenberg, Jean-Francois eChatal, Jacques eBarbet
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-03-01
Series:Frontiers in Pharmacology
Subjects:
Radioimmunotherapy
pretargeting
bispecific antibody
ImmunoPET
Immunoscintigraphy
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00054/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00054/full

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