Cereblon Control of Zebrafish Brain Size by Regulation of Neural Stem Cell Proliferation

Cereblon Control of Zebrafish Brain Size by Regulation of Neural Stem Cell Proliferation

Summary: Thalidomide is a teratogen that causes multiple malformations in the developing baby through its interaction with cereblon (CRBN), a substrate receptor subunit of the CRL4 E3 ubiquitin ligase complex. CRBN was originally reported as a gene associated with autosomal recessive non-syndromic m...

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Main Authors: Hideki Ando, Tomomi Sato, Takumi Ito, Junichi Yamamoto, Satoshi Sakamoto, Nobuhiro Nitta, Tomoko Asatsuma-Okumura, Nobuyuki Shimizu, Ryota Mizushima, Ichio Aoki, Takeshi Imai, Yuki Yamaguchi, Arnold J. Berk, Hiroshi Handa
Format: Article
Language:English
Published: Elsevier 2019-05-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S258900421930104X

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http://www.sciencedirect.com/science/article/pii/S258900421930104X

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