Systematic evaluation of isoform function in literature reports of alternative splicing

Systematic evaluation of isoform function in literature reports of alternative splicing

Abstract Background Although most genes in mammalian genomes have multiple isoforms, an ongoing debate is whether these isoforms are all functional as well as the extent to which they increase the functional repertoire of the genome. To ground this debate in data, it would be helpful to have a corpu...

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Bibliographic Details
Main Authors: Shamsuddin A. Bhuiyan, Sophia Ly, Minh Phan, Brandon Huntington, Ellie Hogan, Chao Chun Liu, James Liu, Paul Pavlidis
Format: Article
Language:English
Published: BMC 2018-08-01
Series:BMC Genomics
Subjects:
Alternative splicing
Functional diversity
Isoform function
Literature curation
Online Access:http://link.springer.com/article/10.1186/s12864-018-5013-2

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http://link.springer.com/article/10.1186/s12864-018-5013-2

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