Contribution of Nrf2 Modulation to the Mechanism of Action of Analgesic and Anti-inflammatory Drugs in Pre-clinical and Clinical Stages

Despite the progress that has occurred in recent years in the development of therapies to treat painful and inflammatory diseases, there is still a need for effective and potent analgesics and anti-inflammatory drugs. It has long been known that several types of antioxidants also possess analgesic a...

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Bibliographic Details
Main Authors: Larissa Staurengo-Ferrari, Stephanie Badaro-Garcia, Miriam S. N. Hohmann, Marília F. Manchope, Tiago H. Zaninelli, Rubia Casagrande, Waldiceu A. Verri
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01536/full