Engineering large cartilage tissues using dynamic bioreactor culture at defined oxygen conditions
Mesenchymal stem cells maintained in appropriate culture conditions are capable of producing robust cartilage tissue. However, gradients in nutrient availability that arise during three-dimensional culture can result in the development of spatially inhomogeneous cartilage tissues with core regions d...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2018-01-01
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Series: | Journal of Tissue Engineering |
Online Access: | https://doi.org/10.1177/2041731417753718 |