Engineering large cartilage tissues using dynamic bioreactor culture at defined oxygen conditions

Mesenchymal stem cells maintained in appropriate culture conditions are capable of producing robust cartilage tissue. However, gradients in nutrient availability that arise during three-dimensional culture can result in the development of spatially inhomogeneous cartilage tissues with core regions d...

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Bibliographic Details
Main Authors: Andrew C Daly, Binulal N Sathy, Daniel J Kelly
Format: Article
Language:English
Published: SAGE Publishing 2018-01-01
Series:Journal of Tissue Engineering
Online Access:https://doi.org/10.1177/2041731417753718