Towards Reduction or Substitution of Cytotoxic DMSO in Biobanking of Functional Bioengineered Megakaryocytes

Towards Reduction or Substitution of Cytotoxic DMSO in Biobanking of Functional Bioengineered Megakaryocytes

Donor platelet transfusion is currently the only efficient treatment of life-threatening thrombocytopenia, but it is highly challenged by immunological, quality, and contamination issues, as well as short shelf life of the donor material. Ex vivo produced megakaryocytes and platelets represent a pro...

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Bibliographic Details
Main Authors: Denys Pogozhykh, Dorothee Eicke, Oleksandr Gryshkov, Willem F. Wolkers, Kai Schulze, Carlos A. Guzmán, Rainer Blasczyk, Constança Figueiredo
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
megakaryocytes
platelets
induced pluripotent stem cells (iPSC)
biobanking
cytotoxicity
mouse model
Online Access:https://www.mdpi.com/1422-0067/21/20/7654

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https://www.mdpi.com/1422-0067/21/20/7654

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