Differential Expression of Sirtuin Family Members in the Developing, Adult, and Aged Rat Brain

Differential Expression of Sirtuin Family Members in the Developing, Adult, and Aged Rat Brain

The sirtuins are NAD+-dependent protein deacetylases and/or ADP-ribosyltransferases that play roles in metabolic homeostasis, stress response and potentially aging. This enzyme family resides in different subcellular compartments, and acts on a number of different targets in the nucleus, cytoplasm a...

Full description

Bibliographic Details
Main Authors: Elena eSidorova-Darmos, Robert G. Wither, Natalya eShulyakova, Carl eFisher, Melanie eRatnam, Michelle eAarts, Lothar eLilge, Philippe P. Monnier, James Howard Eubanks
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-12-01
Series:Frontiers in Aging Neuroscience
Subjects:
Aging
Brain
Sirtuins
development
Neuron
astrocyte
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2014.00333/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnagi.2014.00333/full

Similar Items