Distinct tumor microenvironments of lytic and blastic bone metastases in prostate cancer patients

Distinct tumor microenvironments of lytic and blastic bone metastases in prostate cancer patients

Abstract The most common metastatic lesions of prostate cancer are in bone and can be classified into three distinct pathology subtypes: lytic, blastic, and an indeterminate mixture of both. We investigated a cohort of decalcified formalin-fixed and paraffin-embedded (FFPE) patient specimens from th...

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Bibliographic Details
Main Authors: Claire L. Ihle, Meredith D. Provera, Desiree M. Straign, E. Erin Smith, Susan M. Edgerton, Adrie Van Bokhoven, M. Scott Lucia, Philip Owens
Format: Article
Language:English
Published: BMJ Publishing Group 2019-11-01
Series:Journal for ImmunoTherapy of Cancer
Subjects:
Prostate
Bone metastases
Tumor microenvironment
Digital spatial profiling
Online Access:http://link.springer.com/article/10.1186/s40425-019-0753-3

Internet

http://link.springer.com/article/10.1186/s40425-019-0753-3

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