Pathogenesis of Osteoarthritis: Risk Factors, Regulatory Pathways in Chondrocytes, and Experimental Models

Pathogenesis of Osteoarthritis: Risk Factors, Regulatory Pathways in Chondrocytes, and Experimental Models

As the most common chronic degenerative joint disease, osteoarthritis (OA) is the leading cause of pain and physical disability, affecting millions of people worldwide. Mainly characterized by articular cartilage degradation, osteophyte formation, subchondral bone remodeling, and synovial inflammati...

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Bibliographic Details
Main Authors: Yuchen He, Zhong Li, Peter G. Alexander, Brian D. Ocasio-Nieves, Lauren Yocum, Hang Lin, Rocky S. Tuan
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Biology
Subjects:
osteoarthritis
pathogenesis
experimental model
disease modifying osteoarthritis drugs
microphysiological systems
Online Access:https://www.mdpi.com/2079-7737/9/8/194

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https://www.mdpi.com/2079-7737/9/8/194

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