Biopolymer-nanotube nerve guidance conduit drug delivery for peripheral nerve regeneration: In vivo structural and functional assessment

Biopolymer-nanotube nerve guidance conduit drug delivery for peripheral nerve regeneration: In vivo structural and functional assessment

Peripheral nerve injuries account for roughly 3% of all trauma patients with over 900,000 repair procedures annually in the US. Of all extremity peripheral nerve injuries, 51% require nerve repair with a transected gap. The current gold-standard treatment for peripheral nerve injuries, autograft rep...

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Bibliographic Details
Main Authors: Ohan S. Manoukian, Swetha Rudraiah, Michael R. Arul, Jenna M. Bartley, Jiana T. Baker, Xiaojun Yu, Sangamesh G. Kumbar
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2021-09-01
Series:Bioactive Materials
Subjects:
Peripheral nerve regeneration
Nerve guidance conduit
Sciatic nerve transection
Small-molecule drug delivery
Neurotrophic factor
Functional recovery
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X21000773

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http://www.sciencedirect.com/science/article/pii/S2452199X21000773

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