Dermatopontin in Bone Marrow Extracellular Matrix Regulates Adherence but Is Dispensable for Murine Hematopoietic Cell Maintenance

Dermatopontin in Bone Marrow Extracellular Matrix Regulates Adherence but Is Dispensable for Murine Hematopoietic Cell Maintenance

The hematopoietic marrow microenvironment is composed of multiple cell types embedded in an extracellular matrix (ECM). We have explored marrow ECM using mass spectrometry and found dermatopontin (DPT), a small non-collagenous ECM protein, to be present. We found that DPT cooperates with other ECM p...

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Bibliographic Details
Main Authors: Ashley C. Kramer, Amanda L. Blake, Mandy E. Taisto, Michael J. Lehrke, Beau R. Webber, Troy C. Lund
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:Stem Cell Reports
Subjects:
hematopoietic niche
hematopoiesis
extracellular matrix
decellularization
dermatopontin
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671117303314

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http://www.sciencedirect.com/science/article/pii/S2213671117303314

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