The Intricate Interplay between Epigenetic Events, Alternative Splicing and Noncoding RNA Deregulation in Colorectal Cancer

The Intricate Interplay between Epigenetic Events, Alternative Splicing and Noncoding RNA Deregulation in Colorectal Cancer

Colorectal cancer (CRC) results from a transformation of colonic epithelial cells into adenocarcinoma cells due to genetic and epigenetic instabilities, alongside remodelling of the surrounding stromal tumour microenvironment. Epithelial-specific epigenetic variations escorting this process include...

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Bibliographic Details
Main Authors: Raheleh Amirkhah, Hojjat Naderi-Meshkin, Jaynish S. Shah, Philip D. Dunne, Ulf Schmitz
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Cells
Subjects:
chromatin remodelling
histone modifications
aberrant DNA methylation
long non-coding RNA
microRNA
Online Access:https://www.mdpi.com/2073-4409/8/8/929

Internet

https://www.mdpi.com/2073-4409/8/8/929

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