Adiponectin mediated MHC class II mismatched cardiac graft rejection in mice is IL-4 dependent.

Adiponectin mediated MHC class II mismatched cardiac graft rejection in mice is IL-4 dependent.

BACKGROUND: Adiponectin regulates glucose and fatty-acid metabolism but its role in chronic graft rejection mediated by Th2 cytokines remains ill-defined. METHODOLOGY/PRINCIPAL FINDINGS: Wild type and adiponectin-null mice were used as graft recipients in mouse MHC class II disparate cardiac transpl...

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Bibliographic Details
Main Authors: Daxu Li, Julia Y S Tsang, Jiao Peng, Derek H H Ho, Yee Kwan Chan, Jiang Zhu, Vincent C H Lui, Aimin Xu, Jonathan R Lamb, Paul K H Tam, Yan Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3498365?pdf=render

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http://europepmc.org/articles/PMC3498365?pdf=render

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