Molecular Dynamic Simulation of 3-(5-Chloro-2, 4-dihydroxyphenyl)-pyrazole-4-carboxamide and HSP90 Molecular Chaperone Interaction
The calculation of free energy differences of a system is of great importance as the rate and extent of many if not all chemical and biophysical processes are governed by the nature of underlying free energy landscape. In this study the preferential binding of 3-(5-chloro-2, 4-dihydroxyphenyl)–pyraz...
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| Format: | Article |
| Language: | English |
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Hindawi Limited
2011-01-01
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| Series: | E-Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2011/715861 |