Mitochondrial division/mitophagy inhibitor (Mdivi) ameliorates pressure overload induced heart failure.

We have previously reported the role of anti-angiogenic factors in inducing the transition from compensatory cardiac hypertrophy to heart failure and the significance of MMP-9 and TIMP-3 in promoting this process during pressure overload hemodynamic stress. Several studies reported the evidence of c...

Full description

Bibliographic Details
Main Authors: Srikanth Givvimani, Charu Munjal, Neetu Tyagi, Utpal Sen, Naira Metreveli, Suresh C Tyagi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3313999?pdf=render