Neural defects caused by total and Wnt1-Cre mediated ablation of p120ctn in mice

Neural defects caused by total and Wnt1-Cre mediated ablation of p120ctn in mice

Abstract Background p120 catenin (p120ctn) is an important component in the cadherin-catenin cell adhesion complex because it stabilizes cadherin-mediated intercellular junctions. Outside these junctions, p120ctn is actively involved in the regulation of small GTPases of the Rho family, in actomyosi...

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Bibliographic Details
Main Authors: Tim Pieters, Ellen Sanders, Huiyu Tian, Jolanda van Hengel, Frans van Roy
Format: Article
Language:English
Published: BMC 2020-08-01
Series:BMC Developmental Biology
Subjects:
p120 catenin
Knockout mouse
Wnt1
NTD
Exencephaly
Neural fold closure
Online Access:http://link.springer.com/article/10.1186/s12861-020-00222-4

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http://link.springer.com/article/10.1186/s12861-020-00222-4

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