Evaluation of X Chromosome Inactivation with Respect to HLA Genetic Susceptibility in Rheumatoid Arthritis and Systemic Sclerosis.

Evaluation of X Chromosome Inactivation with Respect to HLA Genetic Susceptibility in Rheumatoid Arthritis and Systemic Sclerosis.

Autoimmune diseases, including rheumatoid arthritis (RA) and systemic sclerosis (SSc) are characterized by a strong genetic susceptibility from the Human Leucocyte Antigen (HLA) locus. Additionally, disorders of epigenetic processes, in particular non-random X chromosome inactivation (XCI), have bee...

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Bibliographic Details
Main Authors: Sami B Kanaan, Onur E Onat, Nathalie Balandraud, Gabriel V Martin, J Lee Nelson, Doua F Azzouz, Isabelle Auger, Fanny Arnoux, Marielle Martin, Jean Roudier, Tayfun Ozcelik, Nathalie C Lambert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4927113?pdf=render

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http://europepmc.org/articles/PMC4927113?pdf=render

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