Rapid Elimination of Blood Alcohol Using Erythrocytes: Mathematical Modeling and In Vitro Study

Rapid Elimination of Blood Alcohol Using Erythrocytes: Mathematical Modeling and In Vitro Study

Erythrocytes (RBCs) loaded with alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALD) can metabolize plasma ethanol and acetaldehyde but with low efficiency. We investigated the rate-limiting factors in ethanol oxidation by these enzymes loaded into RBCs. Mathematical modeling and in vitro ex...

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Bibliographic Details
Main Authors: Yuliya G. Alexandrovich, Elena A. Kosenko, Elena I. Sinauridze, Sergey I. Obydennyi, Igor I. Kireev, Fazoil I. Ataullakhanov, Yuriy G. Kaminsky
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2017/5849593

Internet

http://dx.doi.org/10.1155/2017/5849593

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