Osmotic adaptation of nucleus pulposus cells: the role of aquaporin 1, aquaporin 4 and transient receptor potential vanilloid 4

The microenvironment of the nucleus pulposus is hyperosmotic and fluctuates diurnally due to mechanical loading. Changes in extracellular osmolality result in cell volume alterations, responsiveness to such changes is essential for cellular homeostasis. Aquaporins allow movement of water across cell...

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Bibliographic Details
Main Authors: JW Snuggs, RAD Bunning, CL Le Maitre
Format: Article
Language:English
Published: AO Research Institute Davos 2021-02-01
Series:European Cells & Materials
Subjects:
Online Access:https://www.ecmjournal.org/papers/vol041/pdf/v041a09.pdf