Clinical and molecular characterization of POU3F4 mutations in multiple DFNX2 Chinese families

Clinical and molecular characterization of POU3F4 mutations in multiple DFNX2 Chinese families

Abstract Background Many X-linked non-syndromic hearing loss (HL) cases are caused by various mutations in the POU domain class 3 transcription factor 4 (POU3F4) gene. This study aimed to identify allelic variants of this gene in two Chinese families displaying X-linked inheritance deafness-2 (DFNX2...

Full description

Bibliographic Details
Main Authors: Yu Su, Xue Gao, Sha-Sha Huang, Jing-Ning Mao, Bang-Qing Huang, Jian-Dong Zhao, Dong-Yang Kang, Xin Zhang, Pu Dai
Format: Article
Language:English
Published: BMC 2018-09-01
Series:BMC Medical Genetics
Subjects:
POU3F4
DFNX2
X-linked deafness
Mutation
Online Access:http://link.springer.com/article/10.1186/s12881-018-0630-9

Internet

http://link.springer.com/article/10.1186/s12881-018-0630-9

Similar Items