Increased Proportion of CD226+ B Cells Is Associated With the Disease Activity and Prognosis of Systemic Lupus Erythematosus

Increased Proportion of CD226+ B Cells Is Associated With the Disease Activity and Prognosis of Systemic Lupus Erythematosus

BackgroundCD226, an activating receptor expressed on the surface of natural killer (NK) cells and T cells, is also seen on B cells and CD226 polymorphism is associated with systemic lupus erythematosus (SLE). Because the specific roles of CD226+ B cells in SLE are still unknown, we investigated the...

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Bibliographic Details
Main Authors: Miki Nakano, Masahiro Ayano, Kazuo Kushimoto, Shotaro Kawano, Kazuhiko Higashioka, Shoichiro Inokuchi, Hiroki Mitoma, Yasutaka Kimoto, Mitsuteru Akahoshi, Nobuyuki Ono, Yojiro Arinobu, Koichi Akashi, Takahiko Horiuchi, Hiroaki Niiro
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Immunology
Subjects:
systemic lupus erythematosus
CD226
B cells
lupus low disease activity
lupus nephritis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.713225/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.713225/full

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