Cannabidiol Overcomes Oxaliplatin Resistance by Enhancing NOS3- and SOD2-Induced Autophagy in Human Colorectal Cancer Cells

Cannabidiol Overcomes Oxaliplatin Resistance by Enhancing NOS3- and SOD2-Induced Autophagy in Human Colorectal Cancer Cells

Although oxaliplatin is an effective chemotherapeutic drug for colorectal cancer (CRC) treatment, patients often develop resistance to it. Therefore, a new strategy for CRC treatment is needed. The purpose of this study was to determine the effect of cannabidiol (CBD), one of the components of the c...

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Bibliographic Details
Main Authors: Soyeon Jeong, Bu Gyeom Kim, Dae Yeong Kim, Bo Ram Kim, Jung Lim Kim, Seong Hye Park, Yoo Jin Na, Min Jee Jo, Hye Kyeong Yun, Yoon A. Jeong, Hong Jun Kim, Sun Il Lee, Han Do Kim, Dae Hyun Kim, Sang Cheul Oh, Dae-Hee Lee
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Cancers
Subjects:
oxaliplatin resistance
colorectal cancer
CBD
NOS3
autophagy
mitochondrial dysfunction
Online Access:https://www.mdpi.com/2072-6694/11/6/781

Internet

https://www.mdpi.com/2072-6694/11/6/781

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