Functional dissection of the PE domain responsible for translocation of PE_PGRS33 across the mycobacterial cell wall.

PE are peculiar exported mycobacterial proteins over-represented in pathogenic mycobacterial species. They are characterized by an N-terminal domain of about 110 amino acids (PE domain) which has been demonstrated to be responsible for their export and localization. In this paper, we characterize th...

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Bibliographic Details
Main Authors: Alessandro Cascioferro, Maria H Daleke, Marcello Ventura, Valentina Donà, Giovanni Delogu, Giorgio Palù, Wilbert Bitter, Riccardo Manganelli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3218021?pdf=render