Anti-proliferative and anti-angiogenic activities of ion-channel modulators: In-ovo, in-vitro and in-vivo study

Objective: Angiogenesis is the development of new blood vessels. The ion channels on endothelium play a vital action in cell proliferation and so in the related angiogenesis. We aimed to investigate the anti-angiogenic effects of Mefloquine (Cl− channel blocker) and 4-Aminopyridine (K+ channel block...

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Bibliographic Details
Main Authors: Chandana Kamili, Ravi Shankar Kakataparthy, Uma Maheshwararao Vattikutti, Vijay Chidrawar, Sindhuri Ammineni
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-06-01
Series:Asian Pacific Journal of Tropical Biomedicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S222116911630452X