Bioinformatic Prediction and Introducing of Some Targeting MicroRNAs of Sirt1 and Bcl2 Genes in Model of Parkinson's Disease
Abstract Background: Oxidative Stress and mitochondrial dysfunction leading to apoptotic death of neurons play key role in the pathogenesis of the Parkinson's disease. On the other hand، misregulation of microRNAs can cause several neurodegenerative diseases. Sirt1 and Bcl2 as two key genes, r...
Main Authors: | , , , |
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Format: | Article |
Language: | fas |
Published: |
Arak Medical University
2017-11-01
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Series: | Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk |
Subjects: | |
Online Access: | http://amuj.arakmu.ac.ir/article-1-5213-en.pdf |