Bioinformatic Prediction and Introducing of Some Targeting MicroRNAs of Sirt1 and Bcl2 Genes in Model of Parkinson's Disease

Abstract Background: Oxidative Stress and mitochondrial dysfunction leading to apoptotic death of neurons play key role in the pathogenesis of the Parkinson's disease. On the other hand، misregulation of microRNAs can cause several neurodegenerative diseases. Sirt1 and Bcl2 as two key genes, r...

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Bibliographic Details
Main Authors: Mahsa Rostamian Delavar, Masoud Baghi, Elahe Yadegari, Kamran Ghaedi
Format: Article
Language:fas
Published: Arak Medical University 2017-11-01
Series:Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk
Subjects:
Online Access:http://amuj.arakmu.ac.ir/article-1-5213-en.pdf