Smc5/6 Mediated Sumoylation of the Sgs1-Top3-Rmi1 Complex Promotes Removal of Recombination Intermediates

Smc5/6 Mediated Sumoylation of the Sgs1-Top3-Rmi1 Complex Promotes Removal of Recombination Intermediates

Timely removal of DNA recombination intermediates is critical for genome stability. The DNA helicase-topoisomerase complex, Sgs1-Top3-Rmi1 (STR), is the major pathway for processing these intermediates to generate conservative products. However, the mechanisms that promote STR-mediated functions rem...

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Bibliographic Details
Main Authors: Jaclyn N. Bonner, Koyi Choi, Xiaoyu Xue, Nikko P. Torres, Barnabas Szakal, Lei Wei, Bingbing Wan, Meret Arter, Joao Matos, Patrick Sung, Grant W. Brown, Dana Branzei, Xiaolan Zhao
Format: Article
Language:English
Published: Elsevier 2016-07-01
Series:Cell Reports
Subjects:
recombination intermediates
protein sumoylation
Smc5/6
Sgs1
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716307409

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http://www.sciencedirect.com/science/article/pii/S2211124716307409

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