Induction of Necrosis in Human Macrophage Cell Lines by <i>Corynebacterium diphtheriae</i> and <i>Corynebacterium ulcerans</i> Strains Isolated from Fatal Cases of Systemic Infections

Induction of Necrosis in Human Macrophage Cell Lines by <i>Corynebacterium diphtheriae</i> and <i>Corynebacterium ulcerans</i> Strains Isolated from Fatal Cases of Systemic Infections

When infecting a human host, <i>Corynebacterium diphtheriae</i> and <i>Corynebacterium ulcerans</i> are able to impair macrophage maturation and induce cell death. However, the underlying molecular mechanisms are not well understood. As a framework for this project, a combina...

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Bibliographic Details
Main Authors: Dulanthi Weerasekera, Jonas Hahn, Martin Herrmann, Andreas Burkovski
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:International Journal of Molecular Sciences
Subjects:
cell death
FACS
host-pathogen interaction
live cell imaging
macrophages
THP-1 cells
Online Access:https://www.mdpi.com/1422-0067/20/17/4109

Internet

https://www.mdpi.com/1422-0067/20/17/4109

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