Exposure to CuO Nanoparticles Mediates NFκB Activation and Enhances Amyloid Precursor Protein Expression

Exposure to CuO Nanoparticles Mediates NFκB Activation and Enhances Amyloid Precursor Protein Expression

Amyloid precursor protein (APP) is directly related to Aβ amyloidosis—a hallmark of Alzheimer’s disease (AD). However, the impact of environmental factors upon APP biology and Aβ amyloid pathology have not been well studied. The increased use of nanoparticles (N...

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Bibliographic Details
Main Authors: Xiaoyang Mou, Alexander Pilozzi, Breeya Tailor, Jing Yi, Catherine Cahill, Jack Rogers, Xudong Huang
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Biomedicines
Subjects:
alzheimer’s disease
nfkb
ikba
ab
amyloid precursor protein
nanoparticles
engineered nanomaterials
nanoneurotoxicity
Online Access:https://www.mdpi.com/2227-9059/8/3/45

Internet

https://www.mdpi.com/2227-9059/8/3/45

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