Synthesis and characterization of new branched magnetic nanocomposite for loading and release of topotecan anti-cancer drug

Synthesis and characterization of new branched magnetic nanocomposite for loading and release of topotecan anti-cancer drug

Abstract The purpose of this study is to synthesize the new branched magnetic nanocomposite to carry the therapeutic agents and bio-macromolecules. Although topotecan (TPT) has significant antitumor activity to lung, ovarian, breast, pancreas, and stomach cancers, lactone ring opening causes a reduc...

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Bibliographic Details
Main Authors: Tuba Tarhan, Bilsen Tural, Servet Tural
Format: Article
Language:English
Published: SpringerOpen 2019-09-01
Series:Journal of Analytical Science and Technology
Subjects:
Drug nanocarrier
Drug release
Magnetic nanocomposite
Magnetic targeting
New branched dextran
Topotecan
Online Access:http://link.springer.com/article/10.1186/s40543-019-0189-x

Internet

http://link.springer.com/article/10.1186/s40543-019-0189-x

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